Syntesis and Spectral Studies of Mixed Ligand Complexes of Chloropropamide /Gliclazide with Iron and Cobalt

Arshi Siddiqui and S. A. Iqbal

Department of Chemistry, Saifia College of Science and Education, Bhopal-46 2001 (India)

DOI : http://dx.doi.org/10.13005/msri/030114

ABSTRACT:

Co-ordination compounds of chloropropamide (CPM) N-Propyl-N-(Pchlorobenzene sulphonyl) urea (trade name, diabinese) and gliclazide (GCZ) 1 - (3 - azabicyclo [3,3,0] oct - 3yl) - 3 - (P - totyl sulphonyl) urea. (trade name, diamicron) are oral hypoglycemic were synthesize with iron(II) and cobalt(II), isolated in pure powderd form, yields are substantial. Stoichiometry suggest 1:1:1 ratio between drugs and metal ion. Analytical data of the complexes agrees with the compositions are C10H12ClN2O3S-Fe-C15H20N3O3S 2H2O and C10H12ClN2O3S-Co- C15H20N3O3S.2H2O The general structure assigned to these complexes is supported by infra-red and electronic spectral studies.

KEYWORDS: Complexation chloropropamide; gliclazide; iron and cobalt

Copy the following to cite this article: Siddiqui A, Iqbal S. A. Syntesis and Spectral Studies of Mixed Ligand Complexes of Chloropropamide /Gliclazide with Iron and Cobalt. Mat.Sci.Res.India;3(1)

Copy the following to cite this URL: Siddiqui A, Iqbal S. A. Syntesis and Spectral Studies of Mixed Ligand Complexes of Chloropropamide /Gliclazide with Iron and Cobalt. Mat.Sci.Res.India;3(1). Available from: http://www.materialsciencejournal.org/?p=1372

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