Synthesis, Determination of Partition Coefficient and Antimicrobial Activity of Triazolo Thiadiazinyl Bromocoumarin Derivatives

B.S. Jayshree^a*, A.R. Sahu², M. Srinivasa Murthy² and K.N. Venugopala²

¹Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal - 576 104 (India)

²Department of Pharmaceutical Chemistry, Al-Ameen College of pharmacy, Hosur Road, Bangalore - 560 027 (India)

ABSTRACT:

A series of triazolo-thiadiazinyl bromocoumarins (10a-k) were synthesized and the compounds were characterized by IR, 1H-NMR and Mass spectral analysis. The partition coefficient, a hydrophobic parameter was also determined for the newly synthesized compounds and the same were subjected for their antimicrobial activity.

KEYWORDS: Bromocoumarin; Triazole; Thiadiazine; Antimicrobial activity; Partition coefficient

Copy the following to cite this article: Jayshreea B. S, Sahu A. R, Murthy M. S, Venugopala K. N. Synthesis, Determination of Partition Coefficient and Antimicrobial Activity of Triazolo Thiadiazinyl Bromocoumarin Derivatives. Mat.Sci.Res.India;3(2a)

Copy the following to cite this URL: Jayshreea B. S, Sahu A. R, Murthy M. S, Venugopala K. N. Synthesis, Determination of Partition Coefficient and Antimicrobial Activity of Triazolo Thiadiazinyl Bromocoumarin Derivatives. Mat.Sci.Res.India;3(2a). Available from: http://www.materialsciencejournal.org/?p=3378

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